Tag: XNA
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Are we there yet with XNA aptamers?
Chaillou S, Thonon S, Reynders S, Lescrinier E, Pinheiro VB. RSC Advances (2026).
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Structural insights into the morpholino nucleic acid/RNA duplex using the new XNA builder Ducque in a molecular modeling pipeline
Rihon J, Mattelaer CA, Montalvao RW, Froeyen M, Pinheiro VB, Lescrinier E. Nucleic Acids Research (2024).
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Directed evolution of mesophilic HNA polymerases providing insight into DNA polymerase mechanisms
Handal P, Torres L, Bernardes Pinheiro V. bioRxiv (2022).
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Beneath the XNA world: Tools and targets to build novel biology
Handal-Marquez P, Anupama A, Pezo V, Marlière P, Herdewijn P, Pinheiro VB. Current Opinion in Systems Biology (2020).
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Structural Studies of HNA Substrate Specificity in Mutants of an Archaeal DNA Polymerase Obtained by Directed Evolution
Samson C, Legrand P, Tekpinar M, Rozenski J, Abramov M, Holliger P, Pinheiro VB, Herdewijn P, Delarue M. Biomolecules (2020).
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Kinetic analysis of N-alkylaryl carboxamide hexitol nucleotides as substrates for evolved polymerases
Renders M, Dumbre S, Abramov M, Kestemont D, Margamuljana L, Largy E, Cozens C, Vandenameele J, Bernardes Pinheiro V, Toye…
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Rational design of an XNA ligase through docking of unbound nucleic acids to toroidal proteins
Vanmeert M, Razzokov J, Mirza MU, Weeks SD, Schepers G, Bogaerts A, Rozenski J, Froeyen M, Herdewijn P, Pinheiro V,…
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Methylated Nucleobases: Synthesis and Evaluation for Base Pairing In Vitro and In Vivo
Jabgunde AM, Jaziri F, Bande O, Froeyen M, Abramov M, Hoai N, Schepers G, Lescrinier E, Pinheiro VB, Pezo V,…
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Phosphonomethyl Oligonucleotides as Backbone-Modified Artificial Genetic Polymers
Liu C, Cozens C, Jaziri F, Rozenski J, Marechal A, Dumbre S, Pezo V, Marliere P, Pinheiro VB, Groaz E,…
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XNA Synthesis and Reverse Transcription by Engineered Thermophilic Polymerases
Cozens C, Pinheiro VB. Current Protocols in Chemical Biology (2018).